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Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency.
Papandreou, Apostolos; Singh, Nivedita; Gianfrancesco, Lorita; Budinger, Dimitri; Barwick, Katy; Agrotis, Alexander; Luft, Christin; Shao, Ying; Lenaerts, An-Sofie; Gregory, Allison; Jeong, Suh Young; Hogarth, Penelope; Hayflick, Susan; Barral, Serena; Kriston-Vizi, Janos; Gissen, Paul; Kurian, Manju A; Ketteler, Robin.
Affiliation
  • Papandreou A; Developmental Neurosciences, Zayed Centre for Research into Rare Disease in Children, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Singh N; Laboratory for Molecular Cell Biology, University College London, London, UK.
  • Gianfrancesco L; Department of Neurology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Budinger D; Laboratory for Molecular Cell Biology, University College London, London, UK.
  • Barwick K; Developmental Neurosciences, Zayed Centre for Research into Rare Disease in Children, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Agrotis A; Developmental Neurosciences, Zayed Centre for Research into Rare Disease in Children, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Luft C; Developmental Neurosciences, Zayed Centre for Research into Rare Disease in Children, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Shao Y; Laboratory for Molecular Cell Biology, University College London, London, UK.
  • Lenaerts AS; Laboratory for Molecular Cell Biology, University College London, London, UK.
  • Gregory A; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, UK.
  • Jeong SY; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, UK.
  • Hogarth P; Oregon Health and Science University, Portland, OR, USA.
  • Hayflick S; Oregon Health and Science University, Portland, OR, USA.
  • Barral S; Oregon Health and Science University, Portland, OR, USA.
  • Kriston-Vizi J; Oregon Health and Science University, Portland, OR, USA.
  • Gissen P; Developmental Neurosciences, Zayed Centre for Research into Rare Disease in Children, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Kurian MA; Laboratory for Molecular Cell Biology, University College London, London, UK.
  • Ketteler R; Inborn Errors of Metabolism, Genetics & Genomic Medicine Programme, Great Ormond Street Institute of Child Health, University College London, London, UK.
bioRxiv ; 2023 Sep 13.
Article in En | MEDLINE | ID: mdl-37745522
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Full text: 1 Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: United kingdom
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Full text: 1 Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: United kingdom