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The rate of de novo structural variation is increased in in vitro-produced offspring and preferentially affects the paternal genome.
Lee, Young-Lim; Bouwman, Aniek C; Harland, Chad; Bosse, Mirte; Costa Monteiro Moreira, Gabriel; Veerkamp, Roel F; Mullaart, Erik; Cambisano, Nadine; Groenen, Martien A M; Karim, Latifa; Coppieters, Wouter; Georges, Michel; Charlier, Carole.
Affiliation
  • Lee YL; Unit of Animal Genomics, GIGA-R, Faculty of Veterinary Medicine, University of Liège, B-4000 Liège, Belgium; younglim.lee@uliege.be michel.georges@uliege.be carole.charlier@uliege.be.
  • Bouwman AC; Wageningen University and Research, Animal Breeding, and Genomics, 6708 WG Wageningen, The Netherlands.
  • Harland C; Wageningen University and Research, Animal Breeding, and Genomics, 6708 WG Wageningen, The Netherlands.
  • Bosse M; Unit of Animal Genomics, GIGA-R, Faculty of Veterinary Medicine, University of Liège, B-4000 Liège, Belgium.
  • Costa Monteiro Moreira G; Livestock Improvement Corporation, Hamilton 3240, New Zealand.
  • Veerkamp RF; Wageningen University and Research, Animal Breeding, and Genomics, 6708 WG Wageningen, The Netherlands.
  • Mullaart E; Unit of Animal Genomics, GIGA-R, Faculty of Veterinary Medicine, University of Liège, B-4000 Liège, Belgium.
  • Cambisano N; Wageningen University and Research, Animal Breeding, and Genomics, 6708 WG Wageningen, The Netherlands.
  • Groenen MAM; CRV B.V., 6842 BD Arnhem, The Netherlands.
  • Karim L; GIGA Genomics Platform, GIGA Institute, University of Liège, B-4000 Liège, Belgium.
  • Coppieters W; Wageningen University and Research, Animal Breeding, and Genomics, 6708 WG Wageningen, The Netherlands.
  • Georges M; GIGA Genomics Platform, GIGA Institute, University of Liège, B-4000 Liège, Belgium.
  • Charlier C; Unit of Animal Genomics, GIGA-R, Faculty of Veterinary Medicine, University of Liège, B-4000 Liège, Belgium.
Genome Res ; 33(9): 1455-1464, 2023 09.
Article in En | MEDLINE | ID: mdl-37793781
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Full text: 1 Database: MEDLINE Main subject: Family / Embryonic Development Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Genome Res Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Family / Embryonic Development Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Genome Res Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2023 Type: Article