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Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
Kim, Hyeyeon; Aliar, Kazeera; Tharmapalan, Pirashaanthy; McCloskey, Curtis W; Kuttanamkuzhi, Abhijith; Grünwald, Barbara T; Palomero, Luis; Mahendralingam, Mathepan J; Waas, Matthew; Mer, Arvind S; Elliott, Mitchell J; Zhang, Bowen; Al-Zahrani, Khalid N; Langille, Ellen R; Parsons, Michael; Narala, Swami; Hofer, Stefan; Waterhouse, Paul D; Hakem, Razqallah; Haibe-Kains, Benjamin; Kislinger, Thomas; Schramek, Daniel; Cescon, David W; Pujana, Miquel A; Berman, Hal K; Khokha, Rama.
Affiliation
  • Kim H; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Aliar K; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Tharmapalan P; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • McCloskey CW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Kuttanamkuzhi A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Grünwald BT; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Palomero L; ProCURE, Catalan Institute of Oncology, Oncobell, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Catalonia, Spain.
  • Mahendralingam MJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Waas M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Mer AS; Department of Biochemistry, Microbiology & Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Elliott MJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Zhang B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Al-Zahrani KN; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada.
  • Langille ER; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Parsons M; Department of Biochemistry, Microbiology & Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Narala S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Hofer S; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Waterhouse PD; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Hakem R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 2N2, Canada.
  • Haibe-Kains B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Kislinger T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Schramek D; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Cescon DW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Pujana MA; ProCURE, Catalan Institute of Oncology, Oncobell, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Catalonia, Spain.
  • Berman HK; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Khokha R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 2N2, Canada. Electronic address: r
Cell Rep ; 42(10): 113256, 2023 10 31.
Article in En | MEDLINE | ID: mdl-37847590
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Full text: 1 Database: MEDLINE Main subject: Poly(ADP-ribose) Polymerase Inhibitors / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2023 Type: Article Affiliation country: Canada
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Full text: 1 Database: MEDLINE Main subject: Poly(ADP-ribose) Polymerase Inhibitors / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2023 Type: Article Affiliation country: Canada