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Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance against Inhibitors of Glutamine Metabolism.
Ammar, Nourhane; Hildebrandt, Maya; Geismann, Claudia; Röder, Christian; Gemoll, Timo; Sebens, Susanne; Trauzold, Ania; Schäfer, Heiner.
Affiliation
  • Ammar N; Institute of Experimental Cancer Research University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Bldg. U30, 24105 Kiel, Germany.
  • Hildebrandt M; Institute of Experimental Cancer Research University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Bldg. U30, 24105 Kiel, Germany.
  • Geismann C; Department of Internal Medicine and Gastroenterology, Carl-von-Ossietzky University Oldenburg, Philosophenweg 36, 26121 Oldenburg, Germany.
  • Röder C; TriBanK, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Bldg. U30, 24105 Kiel, Germany.
  • Gemoll T; Section for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
  • Sebens S; Institute of Experimental Cancer Research University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Bldg. U30, 24105 Kiel, Germany.
  • Trauzold A; TriBanK, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Bldg. U30, 24105 Kiel, Germany.
  • Schäfer H; Institute of Experimental Cancer Research University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Bldg. U30, 24105 Kiel, Germany.
Antioxidants (Basel) ; 12(10)2023 Sep 30.
Article in En | MEDLINE | ID: mdl-37891897
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Full text: 1 Database: MEDLINE Language: En Journal: Antioxidants (Basel) Year: 2023 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Language: En Journal: Antioxidants (Basel) Year: 2023 Type: Article Affiliation country: Germany