Your browser doesn't support javascript.
loading
Discovery and Evaluation of C6-Substituted Pyrazolopyrimidine-Based Bisphosphonate Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase and Evaluation of Their Antitumor Efficacy in Multiple Myeloma, Pancreatic Ductal Adenocarcinoma, and Colorectal Cancer.
Boutin, Rebecca; Lee, Hiu-Fung; Guan, Tian Lai; Nguyen, Tan Trieu; Huang, Xian Fang; Waller, Daniel D; Lu, Jordan; Christine Chio, Iok In; Michel, René P; Sebag, Michael; Tsantrizos, Youla S.
Affiliation
  • Boutin R; Department of Chemistry, McGill University, Montreal, Québec H3A 0B8, Canada.
  • Lee HF; Department of Chemistry, McGill University, Montreal, Québec H3A 0B8, Canada.
  • Guan TL; Department of Chemistry, McGill University, Montreal, Québec H3A 0B8, Canada.
  • Nguyen TT; Department of Biochemistry, McGill University, Montreal, Québec H3G 1Y6, Canada.
  • Huang XF; Department of Medicine, McGill University, Montreal, Québec H3A 1A1, Canada.
  • Waller DD; Department of Medicine, McGill University, Montreal, Québec H3A 1A1, Canada.
  • Lu J; Terry Fox Laboratory, BC Cancer Research Institute, Vancouver, British Columbia V5Z 1L3, Canada.
  • Christine Chio II; Institute for Cancer Genetics, Department of Genetics and Development, Columbia University Irving Medical Center, New York, New York 10032, United States.
  • Michel RP; Institute for Cancer Genetics, Department of Genetics and Development, Columbia University Irving Medical Center, New York, New York 10032, United States.
  • Sebag M; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York 10032, United States.
  • Tsantrizos YS; Department of Pathology, McGill University, Montréal, Québec H3A 1A1, Canada.
J Med Chem ; 66(23): 15776-15800, 2023 12 14.
Article in En | MEDLINE | ID: mdl-37982711
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Colorectal Neoplasms / Carcinoma, Pancreatic Ductal / Multiple Myeloma Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Type: Article Affiliation country: Canada
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Colorectal Neoplasms / Carcinoma, Pancreatic Ductal / Multiple Myeloma Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Type: Article Affiliation country: Canada