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In vitro evidence of synergistic efficacy with asciminib combined with reduced dose of ATP-binding pocket tyrosine kinase inhibitors according to the ABL1 kinase domain mutation profile.
Han, Ho-Jae; Kim, Jaeyoon John; Pyne, Danielle; Travas, Anthea; Ambalavanan, Amirthagowri; Kimura, Shinya; Deininger, Michael W; Kim, Jong-Won; Kim, Dennis Dong Hwan.
Affiliation
  • Han HJ; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.
  • Kim JJ; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Pyne D; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Travas A; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Ambalavanan A; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Kimura S; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
  • Deininger MW; Deininger Lab, Versiti Blood Research Institute, Milwaukee, WI, USA.
  • Kim JW; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea. kimjw@skku.edu.
  • Kim DDH; Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. kimjw@skku.edu.
Leukemia ; 38(2): 412-415, 2024 02.
Article in En | MEDLINE | ID: mdl-38155246
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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Niacinamide Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2024 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Niacinamide Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2024 Type: Article