Delayed encephalopathy after acute carbon monoxide poisoning: a case study.
Brain Inj
; 38(5): 331-336, 2024 Apr 15.
Article
in En
| MEDLINE
| ID: mdl-38308510
ABSTRACT
Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is a relatively rare inflammatory-associated neurometabolic complication. In this article, we present a case report of a 50-year-old male patient with a history of carbon monoxide poisoning. This acute poisoning, although successfully controlled during a stay in the intensive care unit of a local hospital, later led to persistent neurological symptoms. The patient was then treated in the inpatient unit of the rehabilitation clinic, where cognitive deterioration began to develop 20 days after admission. Subsequent examination using EEG and magnetic resonance imaging confirmed severe encephalopathy later complicated by SARS-CoV-2 infection with fatal consequences due to bronchopneumonia. Because currently there are no approved guidelines for the management of DEACMP, we briefly discuss the existing challenges for future studies, especially the application of rational immunosuppressive therapy already in the acute treatment phase of CO poisoning, which could prevent the development of a severe form of DEACMP.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Brain Diseases
/
Carbon Monoxide Poisoning
/
Cognition Disorders
Type of study:
Guideline
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Brain Inj
Journal subject:
CEREBRO
Year:
2024
Type:
Article
Affiliation country:
Czech Republic