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Clinical Characteristics and Outcomes of Patients with Heart Failure of Hypertensive Etiology: Analysis of Colombian Heart Failure Registry (RECOLFACA).
Martínez-Carreño, Erika; Echeverría, Luis Eduardo; Rivera-Toquica, Alex; Zarama-Márquez, Mario Hernán; Ramírez-Puentes, Elkin Giovanni; Bustamante, Rafael Ignacio; Palacio, Rolando; Ávila-Barros, Luis Manuel; Campbell-Quintero, Sebastián; Morales-Rodríguez, Lisbeth Natalia; López-Ponce de León, Juan David; Buitrago, Andrés Felipe; Sandoval-Luna, Jorge Alberto; Saldarriaga, Clara; Gómez-Mesa, Juan Esteban.
Affiliation
  • Martínez-Carreño E; Department of Cardiology, Clínica Iberoamérica, Barranquilla, Colombia.
  • Echeverría LE; Department of Cardiology, Fundación Cardiovascular de Colombia, Floridablanca, Colombia.
  • Rivera-Toquica A; Department of Cardiology, Centro Médico para el Corazón, Pereira, Colombia.
  • Zarama-Márquez MH; Department of Cardiology, Clínica los Rosales, Pereira, Colombia.
  • Ramírez-Puentes EG; Department of Cardiology, Universidad Tecnológica de Pereira, Pereira, Colombia.
  • Bustamante RI; Department of Internal Medicine, Clínica Nuestra Señora de Fátima, San Juan de Pasto, Colombia.
  • Palacio R; Department of Cardiology, Sociedad Cardiológica Colombiana S.A.S., Villavicencio, Colombia.
  • Ávila-Barros LM; Department of Cardiology, Rafael Bustamante y Compañía Ltda., Leticia, Colombia.
  • Campbell-Quintero S; Department of Cardiology, Clínica Renacer, Riohacha, Colombia.
  • Morales-Rodríguez LN; Department of Internal Medicine, Clínica Riohacha, Riohacha, Colombia.
  • López-Ponce de León JD; Department of Cardiology, Clínica Medilaser, Florencia, Colombia.
  • Buitrago AF; Department of Cardiology, Clínica Medilaser, Neiva, Colombia.
  • Sandoval-Luna JA; Department of Cardiology, Fundación Valle del Lili, Cali, Colombia.
  • Saldarriaga C; Department of Cardiology, Fundación Santa Fe, Bogotá, Colombia.
  • Gómez-Mesa JE; Department of Cardiology, Cardiologia siglo XXI, Ibagué, Colombia.
Kidney Blood Press Res ; 49(1): 165-172, 2024.
Article in En | MEDLINE | ID: mdl-38359802
ABSTRACT

INTRODUCTION:

Arterial hypertension represents one of the main comorbidities observed in patients with heart failure (HF) and one of the main risk factors for its development. Despite this, studies assessing this hypertensive etiology are scarce in Latin America. Our objective was to analyze the prevalence of HF of hypertensive etiology and evaluate its prognosis in patients enrolled in the Colombian Heart Failure Registry (RECOLFACA by its Spanish acronym).

METHODS:

RECOLFACA recruited adult patients diagnosed with HF in 60 centers in Colombia between 2017 and 2019. The primary outcome was all-cause mortality. A Cox proportional hazards regression model was used to assess factors associated with primary outcomes in patients with hypertensive HF. A p value <0.05 was considered significant. All statistical tests were two-tailed.

RESULTS:

Out of the total number of patients evaluated in RECOLFACA (n = 2,514), 804 had a diagnosis of HF with hypertensive etiology (31.9%). These patients were less frequently males and had a significantly older age and lower prevalence of comorbidities than those with HF of other etiologies. Additionally, patients with hypertensive HF had a higher prevalence of HF with preserved ejection fraction (HFpEF) (34.1% vs. 28.3%; p = 0.004). Finally, type 2 diabetes mellitus, chronic obstructive pulmonary disease diagnosis, and NYHA class IV were classified as independent mortality risk factors.

CONCLUSIONS:

Hypertensive HF represents about one-third of the total number of patients with HF in RECOLFACA. Compared with HF of other etiologies, it presents a differential clinical profile - older age and a higher prevalence of HFpEF. RECOLFACA has become a useful tool to characterize patients with HF in Colombia, with which it has been possible to carry out a more specific search and reach the diagnosis of this pathology in our population, and it has served as an example to stimulate registries of patients with HF in other countries in the region.
Subject(s)
Key words

Full text: 1 Database: MEDLINE Main subject: Registries / Heart Failure / Hypertension Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: America do sul / Colombia Language: En Journal: Kidney Blood Press Res Journal subject: NEFROLOGIA Year: 2024 Type: Article Affiliation country: Colombia

Full text: 1 Database: MEDLINE Main subject: Registries / Heart Failure / Hypertension Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: America do sul / Colombia Language: En Journal: Kidney Blood Press Res Journal subject: NEFROLOGIA Year: 2024 Type: Article Affiliation country: Colombia