Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico.
Ann Hum Biol
; 51(1): 2323037, 2024 Feb.
Article
in En
| MEDLINE
| ID: mdl-38478965
ABSTRACT
BACKGROUND:
Knowledge about the influence of early developmental factors on cardiometabolic health in the Maya is limited.AIM:
To analyse the relationship between birthweight (BW) and cardiometabolic parameters in a sample of rural Maya children from Yucatan, Mexico. SUBJECTS ANDMETHODS:
We took anthropometric measurements and obtained data on BW and fasting blood samples in a sample of 75 children aged 5-14 years. Dependent variables were fat mass index (FMI), body mass index (BMI), glucose (G), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), LDL/HDL and TC/HDL ratios and metabolic index (TGxG/HDL2). Outcomes were transformed to y = 100 log(e)x and the resulting estimates are interpreted as symmetrical percentage differences. The main independent variable was BW z-score. Multiple linear regression analyses were used to assess the relationship between BW and outcomes.RESULTS:
An increase of one standard deviation in BW predicted 6.6% (95% CI [-11.6, -1.6]) decrease in HDL and 11% (95% CI [3.7, 18.4]), 7.8% (95% CI [2.3, 13.2]) and 19.6% (95% CI [3.1, 36]) increases in LDL/HDL, TC/HDL and metabolic index, respectively.CONCLUSION:
Higher birthweights were associated with adverse levels of biochemical parameters in this sample of rural Maya children.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Blood Glucose
/
Cardiovascular Diseases
Limits:
Child
/
Humans
Country/Region as subject:
Mexico
Language:
En
Journal:
Ann Hum Biol
Year:
2024
Type:
Article