Estimating Lumbar Spine Least Significant Change for Fewer than Four Vertebrae: The Manitoba BMD Registry.
J Clin Densitom
; 27(2): 101483, 2024.
Article
in En
| MEDLINE
| ID: mdl-38479135
ABSTRACT
INTRODUCTION:
The International Society of Clinical Densitometry recommends omitting lumbar vertebrae affected by structural artifact from spine BMD measurement. Since reporting fewer than 4 vertebrae reduces spine BMD precision, least significant change (LSC) needs to be adjusted upwards when reporting spine BMD change based on fewer than 4 vertebrae.METHODOLOGY:
In order to simplify estimating LSC from combinations of vertebrae other than L1-L4 (denoted LSCL1-4 ), we analyzed 879 DXA spine scan-pairs from the Manitoba BMD Program's ongoing precision evaluation. The additional impact on the LSC of performing the second scan on the same day vs different day was also assessed.RESULTS:
LSC progressively increased when fewer vertebrae were included, and also increased when the scans were performed on different days. We estimated that the LSCL1-4 should be adjusted upwards by 7â¯%, 24â¯% and 65â¯% to approximate the LSC for 3, 2, or 1 vertebral body, respectively. To additionally capture the greater LSC when the precision study was done on different days, LSCL1-4 derived from a precision study where scans were done on the same day should be adjusted upwards by 39â¯%, 60â¯% and 112â¯% for 3, 2, or 1 vertebral body, respectively.CONCLUSION:
LSCL1-4 derived from a precision study where scans are performed on the same day can be used to estimate LSC for fewer than 4 vertebrae and for scans performed on different days.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Absorptiometry, Photon
/
Bone Density
/
Registries
/
Lumbar Vertebrae
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do norte
Language:
En
Journal:
J Clin Densitom
/
J. clin. densitom
/
Journal of clinical densitometry
Journal subject:
ORTOPEDIA
Year:
2024
Type:
Article
Affiliation country:
United States