A new phenolic compound from <i>Persicaria capitata</i>.

He, Lei; Zhong, Fei; Chen, Xing-Jun; Yang, Ya-Ru; Yan, Xue-Long; He, Ming-Hui; Zhang, Xu; Wang, Mu-Zhen; Zeng, Yong-Qin; Zhu, Qin-Feng; Zeng, Zhu; Tu, Bo; Long, Qing-De; Lin, Yan

A new phenolic compound from Persicaria capitata.

He, Lei; Zhong, Fei; Chen, Xing-Jun; Yang, Ya-Ru; Yan, Xue-Long; He, Ming-Hui; Zhang, Xu; Wang, Mu-Zhen; Zeng, Yong-Qin; Zhu, Qin-Feng; Zeng, Zhu; Tu, Bo; Long, Qing-De; Lin, Yan.

Affiliation

He L; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China.
Zhong F; Engineering Center of Cellular Immunotherapy of Guizhou Province, Guizhou Medical University, Guiyang, China.
Chen XJ; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province, Guizhou Medical University, Guizhou, China.
Yang YR; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China.
Yan XL; Engineering Center of Cellular Immunotherapy of Guizhou Province, Guizhou Medical University, Guiyang, China.
He MH; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province, Guizhou Medical University, Guizhou, China.
Zhang X; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China.
Wang MZ; Engineering Center of Cellular Immunotherapy of Guizhou Province, Guizhou Medical University, Guiyang, China.
Zeng YQ; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province, Guizhou Medical University, Guizhou, China.
Zhu QF; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China.
Zeng Z; Engineering Center of Cellular Immunotherapy of Guizhou Province, Guizhou Medical University, Guiyang, China.
Tu B; University Engineering Research Center for the Prevention and Treatment of Chronic Diseases by Authentic Medicinal Materials in Guizhou Province, Guizhou Medical University, Guizhou, China.
Long QD; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China.
Lin Y; Engineering Center of Cellular Immunotherapy of Guizhou Province, Guizhou Medical University, Guiyang, China.

Nat Prod Res ; : 1-7, 2024 Mar 23.

Article in En | MEDLINE | ID: mdl-38520719

ABSTRACT

ABSTRACT

Persicaria capitata was a frequently used Hmong medicinal flora in China. In this study, one new phenolic compound, capitaone A (1) together with 20 known ones, were isolated from the whole herb of P. capitata. Among them, 7 components (4, 9-11, 15-16, 20-21) were discovered from P. capitata for the first time. Their chemical structures were elucidated on the basis of extensive NMR and MS spectrum. Furthermore, three compounds (15, 20, 21) displayed remarkable cytotoxic activities against two human cancer cell lines (A549 and HepG2).

Key words

Persicaria capitata; cytotoxic activity; phenolic compounds

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