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Postoperative delayed emptying after total, subtotal, or distal gastrectomy for gastric cancer: a population-based study.
Junttila, Anna; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H.
Affiliation
  • Junttila A; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland. Electronic address: anna.junttila@fimnet.fi.
  • Helminen O; Surgery Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Helmiö M; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
  • Huhta H; Surgery Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Jalkanen A; Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Kallio R; Department of Oncology and Haematology, Oulu University Hospital, Oulu, Finland.
  • Koivukangas V; Surgery Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Kokkola A; Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Laine S; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
  • Lietzen E; Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.
  • Louhimo J; Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Meriläinen S; Surgery Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Pohjanen VM; Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.
  • Rantanen T; Department of Surgery, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
  • Ristimäki A; Department of Pathology, HUSLAB, HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Applied Tumor Genomics Research Program, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Räsänen JV; Department of General Thoracic and Oesophageal Surgery, Heart and Lung Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Saarnio J; Surgery Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Sihvo E; Department of Surgery, Central Finland Central Hospital, Jyväskylä, Finland.
  • Toikkanen V; Department of Cardiothoracic Surgery, Heart Center, Tampere University Hospital and University of Tampere, Tampere, Finland.
  • Tyrväinen T; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
  • Valtola A; Department of Surgery, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
  • Kauppila JH; Surgery Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; Division of Upper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
J Gastrointest Surg ; 28(7): 1083-1088, 2024 Jul.
Article in En | MEDLINE | ID: mdl-38705370
ABSTRACT

BACKGROUND:

This study aimed to examine the rate of delayed emptying and other 90-day postoperative complications after total, subtotal, and distal gastrectomies for gastric adenocarcinoma in a population-based setting.

METHODS:

This study included all patients who underwent total, subtotal, or distal gastrectomy for gastric cancer in Finland in 2005-2016, with follow-up until December 31, 2019. Logistic regression provided the odds ratios with 95% CIs of 90-day mortality. The results were adjusted for age, sex, year of surgery, comorbidities, pathologic stage, and neoadjuvant therapy.

RESULTS:

A total of 2058 patients underwent total (n = 1227), subtotal (n = 450), or distal (n = 381) gastrectomy. In the total, subtotal, and distal gastrectomy groups, the rates of 90-day delayed emptying were 1.7%, 1.3%, and 2.1% in the whole cohort and 1.6%, 1.8%, and 3.5% in the subgroup analysis of R0 resections, respectively. The resection type was not associated with the risk of delayed emptying. Subtotal gastrectomy was associated with a lower risk of major complications and reoperations, whereas distal gastrectomy was associated with a lower risk of anastomotic complications.

CONCLUSION:

The extent of resection did not affect delayed emptying, whereas fewer postoperative complications were observed after subtotal or distal gastrectomy than after total gastrectomy.
Subject(s)
Key words

Full text: 1 Database: MEDLINE Main subject: Postoperative Complications / Stomach Neoplasms / Adenocarcinoma / Gastrectomy Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Gastrointest Surg Journal subject: GASTROENTEROLOGIA Year: 2024 Type: Article

Full text: 1 Database: MEDLINE Main subject: Postoperative Complications / Stomach Neoplasms / Adenocarcinoma / Gastrectomy Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: J Gastrointest Surg Journal subject: GASTROENTEROLOGIA Year: 2024 Type: Article