Early predictors of severe left main and/or three-vessel disease in patients with non-ST-segment elevation myocardial infarction: A dual-center retrospective study.
Ann Noninvasive Electrocardiol
; 29(3): e13120, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38706219
ABSTRACT
BACKGROUND:
Early detection of patients concomitant with left main and/or three-vessel disease (LM/3VD) and high SYNTAX score (SS) is crucial for determining the most effective revascularization options regarding the use of antiplatelet medications and prognosis risk stratification. However, there is a lack of study for predictors of LM/3VD with SS in patients with non-ST-segment elevation myocardial infarction (NSTEMI). We aimed to identify potential factors that could predict LM/3VD with high SS (SS > 22) in patients with NSTEMI.METHODS:
This dual-center retrospective study included a total of 481 patients diagnosed with NSTEMI who performed coronary angiography procedures. Clinical factors on admission were collected. The patients were divided into non-LM/3VD, Nonsevere LM/3VD (SS ≤ 22), and Severe LM/3VD (SS > 22) groups. To identify independent predictors, Univariate and logistic regression analyses were conducted on the clinical parameters.RESULTS:
A total of 481 patients were included, with an average age of 60.9 years and 75.9% being male. Among these patients, 108 individuals had severe LM/3VD. Based on the findings of a multivariate logistic regression analysis, the extent of ST-segment elevation observed in lead aVR (OR 7.431, 95% CI 3.862-14.301, p < .001) and age (OR 1.050, 95% CI 1.029-1.071, p < .001) were identified as independent predictors of severe LM/3VD.CONCLUSION:
This study indicated that the age of patients and the extent of ST-segment elevation observed in lead aVR on initial electrocardiogram were the independent predictive factors of LM/3VD with high SS in patients with NSTEMI.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Severity of Illness Index
/
Coronary Angiography
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Non-ST Elevated Myocardial Infarction
Limits:
Aged
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Female
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Humans
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Male
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Middle aged
Language:
En
Journal:
Ann Noninvasive Electrocardiol
Journal subject:
CARDIOLOGIA
Year:
2024
Type:
Article
Affiliation country:
China