Sunscreens Part 1: Mechanisms and Efficacy.

Azim, Sara Abdel; Bainvoll, Liat; Vecerek, Natalia; DeLeo, Vincent A; Adler, Brandon L

Azim, Sara Abdel; Bainvoll, Liat; Vecerek, Natalia; DeLeo, Vincent A; Adler, Brandon L.

Affiliation

Azim SA; Georgetown University School of Medicine, Washington, D.C.
Bainvoll L; Keck School of Medicine, University of Southern California, Los Angeles, CA.
Vecerek N; Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
DeLeo VA; Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Adler BL; Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA. Electronic address: brandon.adler@med.usc.edu.

J Am Acad Dermatol ; 2024 May 19.

Article in En | MEDLINE | ID: mdl-38772426

ABSTRACT

ABSTRACT

As our knowledge of the harmful effects of ultraviolet radiation continues to evolve, sunscreen remains an integral part of a comprehensive photoprotection strategy against multiple endpoints of ultraviolet-mediated damage. Part 1 of this review covers sunscreen active and additive ingredient properties, mechanisms of action and gaps in coverage. Following an overview of sunscreen's efficacy in protecting against sunburn, photocarcinogenesis, photoaging, pigmentary disorders, and idiopathic photodermatoses, we highlight considerations for product use and selection in children and individuals with skin of color.

Key words

actinic keratoses; antioxidants; basal cell carcinoma; chemical filters; encapsulation; inorganic filters; iron oxide; keratinocyte carcinoma; melanoma; melasma; nanoparticles; organic filters; photoaging; photodermatoses; photoprotection; physical filters; pigmentation; squamous cell carcinoma; sunburn; sunscreen; tinted sunscreen; ultraviolet light; visible light

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