Mosquitocidal effect of ivermectin-treated nettings and sprayed walls on Anopheles gambiae s.s.
Sci Rep
; 14(1): 12620, 2024 06 01.
Article
in En
| MEDLINE
| ID: mdl-38824239
ABSTRACT
Ivermectin (IVM) has been proposed as a new tool for malaria control as it is toxic on vectors feeding on treated humans or cattle. Nevertheless, IVM may have a direct mosquitocidal effect when applied on bed nets or sprayed walls. The potential for IVM application as a new insecticide for long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) was tested in this proof-of-concept study in a laboratory and semi-field environment. Laboratory-reared, insecticide-susceptible Kisumu Anopheles gambiae were exposed to IVM on impregnated netting materials and sprayed plastered- and mud walls using cone bioassays. The results showed a direct mosquitocidal effect of IVM on this mosquito strain as all mosquitoes died by 24 h after exposure to IVM. The effect was slower on the IVM-sprayed walls compared to the treated nettings. Further work to evaluate possibility of IVM as a new insecticide formulation in LLINs and IRS will be required.
Full text:
1
Database:
MEDLINE
Main subject:
Ivermectin
/
Mosquito Control
/
Insecticide-Treated Bednets
/
Insecticides
/
Anopheles
Limits:
Animals
Language:
En
Journal:
Sci Rep
Year:
2024
Type:
Article
Affiliation country:
Gambia