Low rate hippocampal delay period activity encodes behavioral experience.
Hippocampus
; 34(8): 422-437, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-38838068
ABSTRACT
Remembering what just happened is a crucial prerequisite to form long-term memories but also for establishing and maintaining working memory. So far there is no general agreement about cortical mechanisms that support short-term memory. Using a classifier-based decoding approach, we report that hippocampal activity during few sparsely distributed brief time intervals contains information about the previous sensory motor experience of rodents. These intervals are characterized by only a small increase of firing rate of only a few neurons. These low-rate predictive patterns are present in both working memory and non-working memory tasks, in two rodent species, rats and Mongolian gerbils, are strongly reduced for rats with medial entorhinal cortex lesions, and depend on the familiarity of the sensory-motor context.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Action Potentials
/
Gerbillinae
/
Hippocampus
/
Memory, Short-Term
Limits:
Animals
Language:
En
Journal:
Hippocampus
Journal subject:
CEREBRO
Year:
2024
Type:
Article
Affiliation country:
Germany