Coronary stent implantation links to the occurrence of eosinophilia and interstitial pneumonia: a case report and systematic review.
BMC Pulm Med
; 24(1): 281, 2024 Jun 17.
Article
in En
| MEDLINE
| ID: mdl-38886703
ABSTRACT
BACKGROUND:
Rapamycin has been extensively utilized for coating coronary artery stents to reduce the occurrence of restenosis, yet there has been limited research on the potential harms of rapamycin-eluting stents. Herein, We report a case of eosinophilia and interstitial pneumonia caused by a cobalt-based alloy stent eluted with rapamycin. CASE PRESENTATION The patient was admitted due to fever, cough, and expectoration symptoms. Previously, the patient had undergone a procedure of percutaneous coronary stent implantation in our hospital's cardiology department, which led to a gradual rise in blood eosinophil count. This time, the eosinophil count was higher than the previous admission. A chest CT scan revealed multiple flocculent density increases in both lungs and bronchiectasis. The rapamycin-eluting stents may have caused eosinophilia and interstitial pneumonia, which improved after administering corticosteroids. A systematic review of relevant literature was conducted to summarize the characteristics of interstitial pneumonia caused by drug-eluting stents.CONCLUSION:
Paclitaxel, everolimus, zotarolimus, and rapamycin are the types of drugs that can lead to drug-eluting stents, and because of the rarity of their onset, clinical doctors must be precise and prompt in diagnosing suspected cases to avoid misdiagnosis and delayed treatment.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Lung Diseases, Interstitial
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Sirolimus
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Eosinophilia
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Drug-Eluting Stents
Limits:
Aged
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Humans
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Male
Language:
En
Journal:
BMC Pulm Med
Year:
2024
Type:
Article
Affiliation country:
China