Coverage of Two-Dose Preemptive Cholera Mass Vaccination Campaign in High-Priority Hotspots in Shashemene, Oromia Region, Ethiopia.
Clin Infect Dis
; 79(Supplement_1): S33-S42, 2024 Jul 12.
Article
in En
| MEDLINE
| ID: mdl-38996035
ABSTRACT
BACKGROUND:
Cholera is a public health priority in Ethiopia. The Ethiopian National Cholera Plan elaborates a multi-year scheme of oral cholera vaccine (OCV) use. Aligned with this, a preemptive OCV campaign was conducted under our Ethiopia Cholera Control and Prevention project. Here, we present the OCV vaccination outcomes.METHOD:
Cholera high-priority hotspots in the Oromia Region, Shashemene Town (ST) and Shashemene Woreda (SW), were selected. Four kebelles (Abosto, Alelu, Arada, and Awasho) in ST and 4 clusters (Faji Gole, Harabate, Toga, and Chabi) in SW were study sites with OCV areas nested within. A total of 40 000 and 60 000 people in ST and SW, respectively, were targeted for a 2-dose OCV (Euvichol-Plus) campaign in 11-15 May (first round [R1]) and 27-31 May (second round [R2]) 2022. Daily administrative OCV coverage and a coverage survey in 277 randomly selected households were conducted.RESULTS:
The administrative OCV coverage was high 102.0% for R1 and 100.5% for R2 in ST and 99.1% (R1) and 100.0% (R1) in SW. The coverage survey showed 78.0% (95% confidence interval [CI] 73.1-82.9) of household members with 2-dose OCV and 16.8% (95% CI 12.4-21.3) with no OCV in ST; and 83.1% (95% CI 79.6-86.5) with 2-dose OCV and 11.8% (95% CI 8.8-14.8) with no OCV in SW. The 2-dose coverages in 1-4-, 5-14-, and ≥15-year age groups were 88.3% (95% CI 70.6-96.1), 88.9% (95% CI 82.1-95.7), and 71.3% (95% CI 64.2-78.3), respectively, in ST and 78.2% (95% CI 68.8-87.7), 91.0% (95% CI 86.6-95.3), and 78.7% (95% CI 73.2-84.1) in SW.CONCLUSIONS:
High 2-dose OCV coverage was achieved. Cholera surveillance is needed to assess the vaccine impact and effectiveness.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Cholera Vaccines
/
Cholera
/
Mass Vaccination
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
Country/Region as subject:
Africa
Language:
En
Journal:
Clin Infect Dis
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2024
Type:
Article