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Reducing racial and ethnic disparities in cardiovascular outcomes among cancer survivors.
Tan, Min Choon; Stabellini, Nickolas; Tan, Jia Yi; Thong, Jia Yean; Hedrick, Catherine; Moore, Justin Xavier; Cullen, Jennifer; Hines, Anika; Sutton, Arnethea; Sheppard, Vanessa; Agarwal, Neeraj; Guha, Avirup.
Affiliation
  • Tan MC; Department of Internal Medicine, New York Medical College at Saint Michael's Medical Center, Newark, NJ, USA.
  • Stabellini N; Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ, USA.
  • Tan JY; Department of Cardiovascular Medicine, Medical College of Georgia at Augusta University, Augusta, GA, USA.
  • Thong JY; Case Western Reserve University School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
  • Hedrick C; Department of Hematology-Oncology, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.
  • Moore JX; Faculdade Israelita de Ciências da Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
  • Cullen J; Department of Internal Medicine, New York Medical College at Saint Michael's Medical Center, Newark, NJ, USA.
  • Hines A; Fudan University Shanghai Medical College, Yangpu District, Shanghai, China.
  • Sutton A; Department of Cardiovascular Medicine, Medical College of Georgia at Augusta University, Augusta, GA, USA.
  • Sheppard V; College of Medicine, University of Kentucky, Lexington, KY, USA.
  • Agarwal N; Case Western Reserve University, Cleveland, OH, USA.
  • Guha A; Virginia Commonwealth University, Richmond, VA, USA.
Curr Oncol Rep ; 2024 Jul 13.
Article in En | MEDLINE | ID: mdl-39002054
ABSTRACT
PURPOSE OF REVIEW Analyze current evidence on racial/ethnic disparities in cardiovascular outcomes among cancer survivors, identifying factors and proposing measures to address health inequities. RECENT

FINDINGS:

Existing literature indicates that the Black population experiences worse cardiovascular outcomes following the diagnosis of both initial primary cancer and second primary cancer, with a notably higher prevalence of cardio-toxic events, particularly among breast cancer survivors. Contributing socioeconomic factors to these disparities include unfavorable social determinants of health, inadequate insurance coverage, and structural racism within the healthcare system. Additionally, proinflammatory epigenetic modification is hypothesized to be a contributing genetic variation factor. Addressing these disparities requires a multiperspective approach, encompassing efforts to address racial disparities and social determinants of health within the healthcare system, refine healthcare policies and access, and integrate historically stigmatized racial groups into clinical research. Racial and ethnic disparities persist in cardiovascular outcomes among cancer survivors, driven by multifactorial causes, predominantly associated with social determinants of health. Addressing these healthcare inequities is imperative, and timely efforts must be implemented to narrow the existing gap effectively.
Key words

Full text: 1 Database: MEDLINE Language: En Journal: Curr Oncol Rep Journal subject: NEOPLASIAS Year: 2024 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Language: En Journal: Curr Oncol Rep Journal subject: NEOPLASIAS Year: 2024 Type: Article Affiliation country: United States