Spontaneous type II cell-derived bronchioloalveolar adenoma in a young ICR mouse.
Lab Anim
; : 236772241257726, 2024 Aug 20.
Article
in En
| MEDLINE
| ID: mdl-39161262
ABSTRACT
Although pulmonary adenomas have been reported in ICR mice, spontaneous adenomas have not been reported in mice aged ≤10 weeks. Here, we report a well-circumscribed nodule (1 mm × 1 mm) in the peripheral lesion of the left lateral lobe of a 10-week-old male ICR mouse. Histopathologic evaluation revealed a well-demarcated nodule compressing the surrounding tissue. The neoplastic cells were polygonal with indistinct cellular borders, round/oval nuclei and abundant cytoplasm. These characteristics led to the diagnosis of type II cell-derived bronchioloalveolar adenoma. Given that they are generally observed in aged laboratory animals, this case represents a rare manifestation of a spontaneous tumor in young laboratory mice before puberty.
Full text:
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Database:
MEDLINE
Language:
En
Journal:
Lab Anim
Year:
2024
Type:
Article