Sleep-like cortical dynamics during wakefulness and their network effects following brain injury.
Nat Commun
; 15(1): 7207, 2024 Aug 22.
Article
in En
| MEDLINE
| ID: mdl-39174560
ABSTRACT
By connecting old and recent notions, different spatial scales, and research domains, we introduce a novel framework on the consequences of brain injury focusing on a key role of slow waves. We argue that the long-standing finding of EEG slow waves after brain injury reflects the intrusion of sleep-like cortical dynamics during wakefulness; we illustrate how these dynamics are generated and how they can lead to functional network disruption and behavioral impairment. Finally, we outline a scenario whereby post-injury slow waves can be modulated to reawaken parts of the brain that have fallen asleep to optimize rehabilitation strategies and promote recovery.
Full text:
1
Database:
MEDLINE
Main subject:
Sleep
/
Wakefulness
/
Brain Injuries
/
Electroencephalography
Limits:
Animals
/
Humans
Language:
En
Journal:
Nat Commun
Journal subject:
BIOLOGIA
/
CIENCIA
Year:
2024
Type:
Article
Affiliation country:
Italy