Developments and Controversies in Invasive Diagnosis of Coronary Microvascular Dysfunction in Angina With Nonobstructive Coronary Arteries.
Mayo Clin Proc
; 99(9): 1469-1481, 2024 Sep.
Article
in En
| MEDLINE
| ID: mdl-39232622
ABSTRACT
Approximately half of all coronary angiograms performed for angina do not show obstructive coronary artery disease, and many of these patients have coronary microvascular dysfunction (CMD). Invasive testing for CMD has increased with the advent and wider availability of thermodilution systems. We review CMD pathophysiology and invasive diagnostic testing using the Doppler and thermodilution systems. We report the results of a PubMed search of invasive microvascular testing and discuss limitations of current diagnostic algorithms in the diagnosis of CMD, including controversies regarding the optimal cutoff value for abnormal coronary flow reserve, use of microvascular resistance indices, and options for increasing sensitivity of testing.
Full text:
1
Database:
MEDLINE
Main subject:
Microcirculation
Limits:
Humans
Language:
En
Journal:
Mayo Clin Proc
/
Mayo clin. proc
/
Mayo clinic proceedings
Year:
2024
Type:
Article