Ultrastructure of gamma-M immunoglobulin and alpha macroglobulin: electron-microscopic study.
Science
; 158(3803): 933-6, 1967 Nov 17.
Article
in En
| MEDLINE
| ID: mdl-4167979
ABSTRACT
Electron microscopy of purified Waldenström macroglobulins and normal human and rabbit gammaM immunoglobulins revealed spider-like structures with five legs varying in length and often joining a central ring. Usually only the central more rigid part of this structure (about 150 by 170 angstroms) was clearly visible, but occasionally particles were seen with longer very flexible legs having a total span of about 350 angstroms. Molecules of gammaM antibody retained antibody activity during preparation for electron microscopy. Human and rabbit alpha macroglobulins revealed more rigid symmetric structures (100 by 200 angstroms) which resembled the Russian letter .
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Database:
MEDLINE
Main subject:
Gamma-Globulins
/
Waldenstrom Macroglobulinemia
Limits:
Animals
/
Humans
Language:
En
Journal:
Science
Year:
1967
Type:
Article