In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.

Mir, G N; Alioto, R L; Sperow, J W; Eash, J R; Krebs, J B; Yelnosky, J

Mir, G N; Alioto, R L; Sperow, J W; Eash, J R; Krebs, J B; Yelnosky, J.

Arzneimittelforschung ; 28(8a): 1448-54, 1978.

Article in En | MEDLINE | ID: mdl-582536

Subject(s)

Amidines/pharmacology; Antidiarrheals; Diphenoxylate/pharmacology; Gastrointestinal Motility/drug effects; Isonipecotic Acids/pharmacology; Loperamide/pharmacology; Piperidines/pharmacology; Animals; Carbachol/pharmacology; Charcoal; Cholera Toxin/pharmacology; Diarrhea/chemically induced; Feces; Male; Prostaglandins E/pharmacology; Rats; Serotonin/pharmacology; Stomach/drug effects

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Database: MEDLINE Main subject: Piperidines / Diphenoxylate / Amidines / Gastrointestinal Motility / Isonipecotic Acids / Loperamide / Antidiarrheals Limits: Animals Language: En Journal: Arzneimittelforschung Year: 1978 Type: Article

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