In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.

Bacchi, C J; Garofalo, J; Mockenhaupt, D; McCann, P P; Diekema, K A; Pegg, A E; Nathan, H C; Mullaney, E A; Chunosoff, L; Sjoerdsma, A; Hutner, S H

Bacchi, C J; Garofalo, J; Mockenhaupt, D; McCann, P P; Diekema, K A; Pegg, A E; Nathan, H C; Mullaney, E A; Chunosoff, L; Sjoerdsma, A; Hutner, S H.

Mol Biochem Parasitol ; 7(3): 209-25, 1983 Mar.

Article in En | MEDLINE | ID: mdl-6193423

Subject(s)

Ornithine/analogs & derivatives; Trypanosomiasis, African/drug therapy; Animals; DNA/biosynthesis; Eflornithine; Female; Kinetics; Macromolecular Substances; Ornithine/administration & dosage; Ornithine/metabolism; Ornithine/pharmacology; Polyamines/biosynthesis; Polyamines/metabolism; Protein Biosynthesis; RNA/biosynthesis; Rats; Rats, Inbred Strains; Trypanosoma brucei brucei/cytology; Trypanosoma brucei brucei/drug effects; Trypanosoma brucei brucei/metabolism; Trypanosomiasis, African/parasitology

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Database: MEDLINE Main subject: Ornithine / Trypanosomiasis, African Limits: Animals Language: En Journal: Mol Biochem Parasitol Year: 1983 Type: Article

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Database: MEDLINE Main subject: Ornithine / Trypanosomiasis, African Limits: Animals Language: En Journal: Mol Biochem Parasitol Year: 1983 Type: Article