Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1.

Kominato, Y; Galson, D; Waterman, W R; Webb, A C; Auron, P E

Kominato, Y; Galson, D; Waterman, W R; Webb, A C; Auron, P E.

Affiliation

Kominato Y; Center for Blood Research, Brigham and Women's Hospital, Boston, Massachusetts.

Mol Cell Biol ; 15(1): 58-68, 1995 Jan.

Article in En | MEDLINE | ID: mdl-7799967

Subject(s)

DNA-Binding Proteins/metabolism; Interleukin-1/genetics; Monocytes/physiology; Promoter Regions, Genetic; Animals; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Consensus Sequence; DNA Mutational Analysis; Gene Expression Regulation; HeLa Cells; Humans; In Vitro Techniques; Mice; Molecular Sequence Data; Nuclear Proteins/metabolism; RNA, Messenger/genetics; Retroviridae Proteins, Oncogenic; Sequence Alignment; Sequence Deletion; Sequence Homology, Nucleic Acid; Transcription, Genetic; Transcriptional Activation

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Full text: 1 Database: MEDLINE Main subject: Monocytes / Interleukin-1 / Promoter Regions, Genetic / DNA-Binding Proteins Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 1995 Type: Article

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