[Qualitative and quantitative studies of 1000 cases of isolated ventricular septal defect and follow-up using two-dimensional color Doppler echocardiography].

ABSTRACT

Color Doppler echocardiography (CDE) was used to evaluate 1,000 cases of isolated ventricular septal defect (IVSD). The types of IVSD included perimembrane (854), outflow tract (131) and muscular (15). Compared to surgical findings, CDE had 100% of sensitivity in the diagnosis of IVSD. The accuracy was 98.0% in determining the types of IVSD. CDE was significantly correlated with surgery in assessing sizes of defects (r = 0.893, P < 0.001). Continuous wave Doppler was significantly correlated with catheterization in measuring pulmonary systolic pressure (r = 0.838, P < 0.001). MPA/Ao value > 1.27 and enlargement of right ventricle were both considered good indices for reflecting pulmonary hypertension. A follow-up datum showed that 21 out of 80 cases of IVSD were closed spontaneously in their age of 7 months to 8 years, and the spontaneous closure was related to the types of defects. The complications of IVSD were also discussed.