Effects of L- and D-arginine and some related esters on the cytosolic mechanisms of alpha-thrombin-induced human platelet activation.

Failli, P; Cecchi, E; Ruocco, C; Fazzini, A; Giotti, A

Failli, P; Cecchi, E; Ruocco, C; Fazzini, A; Giotti, A.

Affiliation

Failli P; Dipartimento di Farmacologia Preclinica e Clinica M. Aiazzi Mancini, University of Florence, Italy.

Br J Pharmacol ; 110(1): 213-8, 1993 Sep.

Article in En | MEDLINE | ID: mdl-8220881

Subject(s)

Arginine/pharmacology; Cytosol/metabolism; Platelet Activation/drug effects; Thrombin/pharmacology; Adenosine Diphosphate/pharmacology; Apyrase/pharmacology; Arachidonic Acids/pharmacology; Arginine/analogs & derivatives; Blood Platelets/drug effects; Blood Platelets/metabolism; Cyclic GMP/blood; Cytosol/drug effects; Humans; In Vitro Techniques; Indomethacin/pharmacology; Kinetics; Nitroprusside/pharmacology; Platelet Aggregation Inhibitors/pharmacology; Sodium-Hydrogen Exchangers/antagonists & inhibitors; Sodium-Hydrogen Exchangers/metabolism; Spectrometry, Fluorescence; Stereoisomerism

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Full text: 1 Database: MEDLINE Main subject: Arginine / Thrombin / Platelet Activation / Cytosol Limits: Humans Language: En Journal: Br J Pharmacol Year: 1993 Type: Article Affiliation country: Italy

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