The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

Smit, L S; Meyer, D J; Billestrup, N; Norstedt, G; Schwartz, J; Carter-Su, C

Smit, L S; Meyer, D J; Billestrup, N; Norstedt, G; Schwartz, J; Carter-Su, C.

Affiliation

Smit LS; Department of Physiology, University of Michigan, Ann Arbor 49109-0622, USA.

Mol Endocrinol ; 10(5): 519-33, 1996 May.

Article in En | MEDLINE | ID: mdl-8732683

Subject(s)

DNA-Binding Proteins/metabolism; Growth Hormone/pharmacology; Interleukin-6; Milk Proteins; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins; Receptors, Somatotropin/physiology; Animals; Base Sequence; CHO Cells/metabolism; Cell Line; Cricetinae; Growth Inhibitors/pharmacology; Humans; Interferon-gamma/pharmacology; Janus Kinase 1; Janus Kinase 2; Leukemia Inhibitory Factor; Lymphokines/pharmacology; Molecular Sequence Data; Phosphotyrosine/metabolism; Receptors, Somatotropin/chemistry; Receptors, Somatotropin/genetics; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Signal Transduction; Structure-Activity Relationship; Trans-Activators/metabolism

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Database: MEDLINE Main subject: Receptors, Somatotropin / Protein-Tyrosine Kinases / Growth Hormone / Proto-Oncogene Proteins / Interleukin-6 / DNA-Binding Proteins / Milk Proteins Limits: Animals / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1996 Type: Article Affiliation country: United States

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