Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.

Delpy, E; Coste, H; Gouville, A C

Delpy, E; Coste, H; Gouville, A C.

Affiliation

Delpy E; Laboratoires GLAXOWELLCOME, Centre de Recherches, Les Ulis, France.

Br J Pharmacol ; 119(3): 471-8, 1996 Oct.

Article in En | MEDLINE | ID: mdl-8894166

Subject(s)

Allopurinol/analogs & derivatives; Cyclic AMP/metabolism; Cyclic GMP/metabolism; Muscle Relaxation/drug effects; Phosphodiesterase Inhibitors/pharmacology; Adrenergic beta-Agonists/pharmacology; Allopurinol/pharmacology; Animals; Aorta, Thoracic/drug effects; Cells, Cultured/drug effects; Colforsin/pharmacology; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol/pharmacology; Male; Muscle Contraction/drug effects; Muscle Relaxation/physiology; Muscle, Smooth, Vascular/drug effects; NG-Nitroarginine Methyl Ester/pharmacology; Nitroprusside/pharmacology; Rats; Vasodilator Agents/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Allopurinol / Cyclic AMP / Cyclic GMP / Muscle Relaxation Limits: Animals Language: En Journal: Br J Pharmacol Year: 1996 Type: Article Affiliation country: France

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