Progesterone inhibits 20alpha-hydroxysteroid dehydrogenase expression in the rat corpus luteum through the glucocorticoid receptor.

Sugino, N; Telleria, C M; Gibori, G

Sugino, N; Telleria, C M; Gibori, G.

Affiliation

Sugino N; Department of Physiology and Biophysics, University of Illinois at Chicago, 60612-7342, USA.

Endocrinology ; 138(10): 4497-500, 1997 Oct.

Article in En | MEDLINE | ID: mdl-9322971

Subject(s)

20-Hydroxysteroid Dehydrogenases/analysis; 20-Hydroxysteroid Dehydrogenases/genetics; Corpus Luteum/enzymology; Gene Expression Regulation, Enzymologic/drug effects; Progesterone/pharmacology; Receptors, Glucocorticoid/drug effects; Animals; Base Sequence; Cell Line, Transformed; Corpus Luteum/cytology; Corpus Luteum/drug effects; DNA/analysis; DNA/chemistry; DNA/genetics; Dexamethasone/pharmacology; Dose-Response Relationship, Drug; Down-Regulation/drug effects; Female; Flow Cytometry; Mifepristone/pharmacology; Polymerase Chain Reaction; Pregnancy; Progesterone/metabolism; RNA, Messenger/analysis; RNA, Messenger/chemistry; RNA, Messenger/genetics; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid/antagonists & inhibitors; Receptors, Glucocorticoid/physiology; Receptors, Progesterone/analysis; Receptors, Progesterone/antagonists & inhibitors; Receptors, Progesterone/drug effects

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Database: MEDLINE Main subject: Progesterone / Receptors, Glucocorticoid / Gene Expression Regulation, Enzymologic / Corpus Luteum / 20-Hydroxysteroid Dehydrogenases Limits: Animals / Pregnancy Language: En Journal: Endocrinology Year: 1997 Type: Article Affiliation country: United States

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