Plasma (1-->3)-beta-D-glucan measurement and polymerase chain reaction on sputum as practical parameters in Pneumocystis carinii pneumonia.
Intern Med
; 37(7): 618-21, 1998 Jul.
Article
in En
| MEDLINE
| ID: mdl-9711891
ABSTRACT
We report a case of Pneumocystis carinii pneumonia in a patient with acquired immunodeficiency syndrome diagnosed and monitored with polymerase chain reaction (PCR) for Pneumocystis carinii on sputum and measurement of plasma (1-->3)-beta-D-glucan (G-test). Results of both studies paralleled the clinical and radiographic improvement. However, the plasma (1-->3)-beta-D-glucan level remained higher than normal when PCR for Pneumocystis carinii became negative in sputum. Both PCR for Pneumocystis carinii on sputum and measurement of plasma (1-->3)-beta-D-glucan are useful for noninvasive diagnosis and monitoring of Pneumocystis carinii, although further investigation is necessary to quantify their relationship.
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Database:
MEDLINE
Main subject:
Pneumocystis
/
Pneumonia, Pneumocystis
/
Sputum
/
Polymerase Chain Reaction
/
AIDS-Related Opportunistic Infections
/
Beta-Glucans
/
Glucans
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Intern Med
Journal subject:
MEDICINA INTERNA
Year:
1998
Type:
Article