Fibrosis hepática congénita: un espectro clínico variable. Casos clínicos / Congenital hepatic fibrosis: report of five cases
Rev. méd. Chile
; 132(6): 733-741, jun. 2004. ilus
Article
en Es
| LILACS
| ID: lil-384222
Biblioteca responsable:
CL12.1
ABSTRACT
Background:
Congenital hepatic fibrosis (CHF) is an autosomic dominant disease that has been associated with polycystic kidney disease.Aim:
To describe the medical management of 5 children with CHF and to evaluate the presence and extension of the associated renal disease. Patients andmethods:
Retrospective review of the medical charts of 5 children with CHF, aged 2 to 14 years.Results:
Three children presented autosomic recessive polycystic kidney disease, which was diagnosed before the appearance of liver disease manifestations. They presented a more severe liver damage, with a more aggressive clinical course requiring use of transjugular intrahepatic porto-systemic shunts (TIPS) or surgical porto-systemic shunts to control portal hypertension. The other two children, in whom the diagnosed was based on asymptomatic hepatomegaly, had normal renal function and structure with a more benign clinical course.Conclusions:
The diagnosis of CHF should be suspected not only in children with polycystic kidney disease but in those children with persistent, hard consistency, left lobe predominance hepatomegaly (Rev Méd Chile 2004; 132 733-41).
Texto completo:
1
Bases de datos:
LILACS
Asunto principal:
Hígado
/
Cirrosis Hepática
Tipo de estudio:
Etiology_studies
Límite:
Adolescent
/
Child
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Child, preschool
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2004
Tipo del documento:
Article
País de afiliación:
Chile