Erythrocyte P1 group antigen expression in VTEC-associated hemolytic uremic syndrome.
Clin Nephrol
; 51(2): 73-6, 1999 Feb.
Article
en En
| MEDLINE
| ID: mdl-10069641
ABSTRACT
BACKGROUND:
The P1 blood group antigen has been postulated as a protective host factor against the development of the verotoxin-associated with hemolytic uremic syndrome (HUS). PATIENTS ANDMETHODS:
In this study the P1 blood group antigen in 59 Japanese children with a past history of hemorrhagic colitis (HC) was scored with a direct agglutination method using a commercial anti P1 antibody.RESULTS:
The P1 antigen was positive in 4 (21.1%) of 19 patients with a history of postdiarrheal HUS and in 11 (28.0%) of 40 patients with no history. There were no significant differences in the frequency of the P1 phenotype between the 2 groups (p = 0.629).CONCLUSION:
We concluded that the P1 blood group antigen is not a protective factor against the development of HUS from verotoxin-producing Escherichia coli(VTEC)-infected hemorrhagic colitis in Japanese individuals.
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Bases de datos:
MEDLINE
Asunto principal:
Sistema del Grupo Sanguíneo P
/
Escherichia coli O157
/
Infecciones por Escherichia coli
/
Síndrome Hemolítico-Urémico
Tipo de estudio:
Risk_factors_studies
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Clin Nephrol
Año:
1999
Tipo del documento:
Article
País de afiliación:
Japón