Fetoscopy in the pregnant rabbit at midgestation.
Fetal Diagn Ther
; 14(2): 118-21, 1999.
Article
en En
| MEDLINE
| ID: mdl-10085511
ABSTRACT
OBJECTIVE:
To develop a small animal model for fetoscopy.METHODS:
In 12 time-dated pregnant rabbits at 22 days' gestational age (term 32 days) one amniotic sac in each uterine horn (n = 24) was used for a fetoscopic procedure. After laparotomy, a 2- to 3-mm microsurgical myometrial incision was made to expose the chorionic and amniotic membrane. Under microscopic control, a 2-mm needle was inserted into the amniotic sac. Through this a 1.2-mm endoscope was passed to carry out fetoscopy during maximally 10 min, using 5-10 ml saline amnioinfusion. Mean outcome measurements were ability to visualize the placenta, umbilical cord and the different fetal elements during fetoscopy, as well as fetal survival and weight at second-look operation at 30 days. The untreated amniotic sacs served as negative controls.RESULTS:
In all cases, fetoscopy could be carried out successfully, and all fetuses survived till delivery without significant influence on fetal birth weight.CONCLUSION:
The midgestational rabbit can be used to perform fetoscopy.
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Bases de datos:
MEDLINE
Asunto principal:
Edad Gestacional
/
Fetoscopía
Límite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Fetal Diagn Ther
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
OBSTETRICIA
/
PERINATOLOGIA
Año:
1999
Tipo del documento:
Article
País de afiliación:
Bélgica