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[The problem of therapeutic efficacy indices. 2. Description of the indices]. / Aperçu sur la problématique des indices d'efficacité thérapeutique, 2: description des indices.
Boissel, J P; Buyse, M; Cucherat, M; Boutitie, F; Gueyffier, F; Chatellier, G; Li, W; Nony, P; Haugh, M; Mignot, G.
Afiliación
  • Boissel JP; Service de pharmacologie clinique, EA 643, Université Claude Bernard, Lyon, France.
Therapie ; 54(3): 309-14, 1999.
Article en Fr | MEDLINE | ID: mdl-10500443
The four indices for a binary outcome or therapeutic objective are: the odds ratio, the relative risk, the absolute benefit and the number of patients to treat. For a continuous outcome, the effect size is the best choice. The odds ratio approximates the relative risk. The difference may be large in some instances. The number of patients to treat is the reciprocal of the absolute benefit. Although they are built on the same two quantities, they are not interchangeable and should not be considered in the same way. Moreover, their meaning is not straightforward and they can be misused.
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Bases de datos: MEDLINE Asunto principal: Resultado del Tratamiento Tipo de estudio: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: Fr Revista: Therapie Año: 1999 Tipo del documento: Article País de afiliación: Francia
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Bases de datos: MEDLINE Asunto principal: Resultado del Tratamiento Tipo de estudio: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: Fr Revista: Therapie Año: 1999 Tipo del documento: Article País de afiliación: Francia