Sarcomere tension-stiffness relation during the tetanus rise in single frog muscle fibres.
J Muscle Res Cell Motil
; 20(5-6): 469-76, 1999 Aug.
Article
en En
| MEDLINE
| ID: mdl-10555065
ABSTRACT
The sarcomere stiffness was measured in single muscle fibres during the development of tetanic tension using a method insensitive to fibre inertia and viscosity. The stiffness was calculated by measuring the ratio between tension and sarcomere length during a period of fast sarcomere elongation at constant velocity. Tension changes were corrected for force truncation by the quick recovery mechanism. The results show that the relation between force and stiffness deviates from the direct proportionality less than previously reported. If the deviation is due to the presence of a linear myofilament compliance in series with the cross-bridges, our data suggest that myofilament compliance accounts for about 30% of the sarcomere compliance. This value is significantly smaller than 50-70% determined by X-ray diffraction measurements. These two different findings, however, may be reconciled by assuming that the myofilament compliance is non-linear increasing appropriately at low tension.
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Bases de datos:
MEDLINE
Asunto principal:
Sarcómeros
/
Fibras Musculares Esqueléticas
/
Contracción Muscular
Límite:
Animals
Idioma:
En
Revista:
J Muscle Res Cell Motil
Año:
1999
Tipo del documento:
Article
País de afiliación:
Italia