[Parkinsonian syndromes in Medellin (Colombia)]. / Síndromes parkinsonianos en Medellín (Colombia).
Rev Neurol
; 31(10): 936-43, 2000.
Article
en Es
| MEDLINE
| ID: mdl-11244687
ABSTRACT
INTRODUCTION:
The definition of parkinsonian syndromes is based on clinical criteria.OBJECTIVE:
To determine the frequency and management of parkinsonism, using criteria of inclusion and exclusion. PATIENTS ANDMETHODS:
We selected 302 consecutive patients, 147 females and 155 males, with parkinsonism, age 66.8 (11.4) (range 13-90), grades of education 7.5 (4.3) (range 0-20). A structured and quantitative protocol was applied to the sample.RESULTS:
The most frequent parkinsonian syndrome was the defined idiopathic Parkinson's disease with 132 participants (43.7%). Probably idiopathic Parkinson's disease was found in 60 cases (19.9%), and possible idiopathic Parkinson's disease in eight cases (2.6%); early onset Parkinson's disease in 10 cases (3.3%), juvenile Parkinson's disease in one case (0.3%), familial Parkinson's disease in five cases (1.7%); cortical Lewy body disease in 16 cases (5.4%), progressive supranuclear palsy in nine cases (3.3%), multiple systemic atrophy in eight cases (2.6%). Secondary Parkinson's disease was distributed as follow vascular disease in 24 cases (8%), local lesion in 11 cases (3%), medications in 16 cases (5.3%), meningoencephalitis in one case (0.3%) and syphilis in one case (0.3%). Without medication was found 1.5% of sample, which was in Hoehn & Yarh's state I to II. In monotherapy was found 23.2%, with two medications 46.7%, with three 23.5% and with four drugs 5.1%. Levodopa was prescript to 70.9%, anticholinergic to 51.3%, MAO-B-I to 33.4%, amantadine to 33.1%, D2 stimulants to 18.5%, and COMT-I to 2.6%.CONCLUSION:
Structured protocol for assessment of parkinsonian syndromes allows reliable diagnoses for clinical and epidemiological purposes.
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Bases de datos:
MEDLINE
Asunto principal:
Trastornos Parkinsonianos
Tipo de estudio:
Etiology_studies
/
Guideline
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
America do sul
/
Colombia
Idioma:
Es
Revista:
Rev Neurol
Año:
2000
Tipo del documento:
Article
País de afiliación:
Colombia