Genotoxic effects and chemical compositions of four creosotes.
Mutat Res
; 265(2): 223-36, 1992 Feb.
Article
en En
| MEDLINE
| ID: mdl-1370721
ABSTRACT
Four creosotes used in Finland for impregnating wood were tested in the Ames Salmonella test, the SCE test and the SOS chromotest. Compounds volatile at 37 degrees C were assayed using the taped plate testing protocol. The creosotes were fractionated according to their natural boiling ranges and the fractions were tested in the Ames Salmonella assay. Chemical compositions of creosotes and fractions were determined by high resolution gas chromatography/mass spectrophotometry techniques and by reversed phase high performance liquid chromatography. Mutagenic activities were shown to reside in fractions having the highest boiling point ranges (greater than 290 degrees C). The concentrations of mutagenic polycyclic aromatic hydrocarbons in creosotes and in some of their corresponding distillation fractions, when compared with mutagenic activities, indicated synergistic or antagonistic interactions.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Creosota
Límite:
Animals
Idioma:
En
Revista:
Mutat Res
Año:
1992
Tipo del documento:
Article
País de afiliación:
Finlandia