Autolysis of Porphyromonas gingivalis is accompanied by an increase in several periodontal pathogenic factors in the supernatant.
Microbiol Immunol
; 48(7): 541-5, 2004.
Article
en En
| MEDLINE
| ID: mdl-15272200
ABSTRACT
Porphyromonas gingivalis autolyzes in the culture media. To examine in more detail the molecular components of the autolysate, two-dimensional gel electrophoresis was performed. Many protein spots varied both in number and volume. One of these spots included Arg-gingipain (Rgp) as determined by N-terminal amino acid sequencing. Corresponding to the increase in spot volume, Rgp activity also increased during autolysis. The results of this study suggested that Rgp and other proteins in the P. gingivalis autolysate may be involved with the prolongation of periodontal disease, even after the death of P. gingivalis cells.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Bacteriólisis
/
Porphyromonas gingivalis
/
Factores de Virulencia
Límite:
Humans
Idioma:
En
Revista:
Microbiol Immunol
Año:
2004
Tipo del documento:
Article
País de afiliación:
Japón