Endocrine control of body composition in infancy, childhood, and puberty.
Endocr Rev
; 26(1): 114-46, 2005 Feb.
Article
en En
| MEDLINE
| ID: mdl-15689575
ABSTRACT
Body composition exhibits marked variations across the early human lifetime. The precise physiological mechanisms that drive such developmental adaptations are difficult to establish. This clinical challenge reflects an array of potentially confounding factors, such as marked intersubject differences in tissue compartments; the incremental nature of longitudinal intrasubject variations in body composition; technical limitations in quantitating the unobserved mass of mineral, fat, water, and muscle ad seriatim; and the multifold contributions of genetic, dietary, environmental, hormonal, nutritional, and behavioral signals to physical and sexual maturation. From an endocrine perspective (reviewed here), gonadal sex steroids and GH/IGF-I constitute prime determinants of evolving body composition. The present critical review examines hormonal regulation of body composition in infancy, childhood, and puberty.
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Bases de datos:
MEDLINE
Asunto principal:
Composición Corporal
/
Pubertad
/
Sistema Endocrino
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Endocr Rev
Año:
2005
Tipo del documento:
Article
País de afiliación:
Estados Unidos