Chemokine response in children with SARS.

Ng, P C; Lam, C W K; Li, A M; Wong, C K; Leung, T F; Cheng, F W T; Hon, K L E; Chan, I H S; Wong, E; Fok, T F

Ng, P C; Lam, C W K; Li, A M; Wong, C K; Leung, T F; Cheng, F W T; Hon, K L E; Chan, I H S; Wong, E; Fok, T F.

Afiliación

Ng PC; Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories. pakcheungng@cuhk.edu.hk

Arch Dis Child ; 90(4): 422-3, 2005 Apr.

Article en En | MEDLINE | ID: mdl-15781938

ABSTRACT

ABSTRACT

The chemokine response of eight children with serologically confirmed severe acute respiratory syndrome (SARS) was longitudinally monitored. All had raised plasma interferon gamma inducible protein (IP-10) concentrations, which suggested an active type 1 T-helper lymphocyte mediated immune response. High circulating IP-10 levels could facilitate viral clearance and might play a role in assisting the recovery of the patients.

Asunto(s)

Quimiocinas/metabolismo; Síndrome Respiratorio Agudo Grave/sangre; Quimiocina CCL2/metabolismo; Quimiocina CCL5/metabolismo; Quimiocina CXCL10; Quimiocina CXCL9; Quimiocinas CXC/metabolismo; Niño; Humanos; Péptidos y Proteínas de Señalización Intercelular/metabolismo; Interferón gamma/metabolismo; Estudios Longitudinales; Linfocitos T/metabolismo

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quimiocinas / Síndrome Respiratorio Agudo Grave Tipo de estudio: Observational_studies Límite: Child / Humans Idioma: En Revista: Arch Dis Child Año: 2005 Tipo del documento: Article

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