alpha-MSH enhances activity-based anorexia.
Peptides
; 26(10): 1690-6, 2005 Oct.
Article
en En
| MEDLINE
| ID: mdl-15964664
ABSTRACT
Activity-based anorexia (ABA) is considered an animal model of anorexia nervosa (AN). In ABA, scheduled feeding in combination with voluntary access to running wheels, results in hyperactivity, hypophagia, body weight loss and activation of the HPA axis. Since stimulation of the melanocortin (MC) system has similar effects, this system is a candidate system involved in ABA. Here it is shown that chronic alpha-MSH treatment enhances ABA by increasing running wheel activity (RWA), decreasing food intake and increasing HPA axis activation.
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Bases de datos:
MEDLINE
Asunto principal:
Alfa-MSH
/
Anorexia
/
Esfuerzo Físico
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Peptides
Año:
2005
Tipo del documento:
Article
País de afiliación:
Países Bajos