Comparison of redox and D29 phage methods for detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis.
Clin Microbiol Infect
; 12(3): 293-6, 2006 Mar.
Article
en En
| MEDLINE
| ID: mdl-16451420
ABSTRACT
Rapid, accurate and inexpensive methods are essential to detect drug-resistant Mycobacterium tuberculosis and allow timely application of effective treatment and precautions to prevent transmission. The proportion method, the MTT and Alamar Blue redox methods, and the D29 mycobacteriophage assay, were compared for their ability to detect resistance to isoniazid and rifampicin. When tested against a panel of known M. tuberculosis strains, the redox methods and the D29 assay showed good sensitivity and specificity compared to the proportion method, suggesting that they could be useful alternatives for identifying multidrug resistance in M. tuberculosis.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Rifampin
/
Pruebas de Sensibilidad Microbiana
/
Isoniazida
/
Mycobacterium tuberculosis
/
Antituberculosos
Tipo de estudio:
Diagnostic_studies
/
Health_economic_evaluation
Idioma:
En
Revista:
Clin Microbiol Infect
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Brasil