Cost-effectiveness of on-site antenatal screening to prevent congenital syphilis in rural eastern Cape Province, Republic of South Africa.
Sex Transm Dis
; 34(7 Suppl): S61-6, 2007 Jul.
Article
en En
| MEDLINE
| ID: mdl-17308502
ABSTRACT
OBJECTIVES:
On-site screening and same-day treatment of maternal syphilis in underresourced settings can avert greater numbers of congenital syphilis cases, but health outcomes and associated costs must be evaluated jointly.METHODS:
We used decision analysis to estimate the incremental cost-effectiveness of two on-site antenatal syphilis screening strategies to avert congenital infections-qualitative RPR (on-site RPR) and treponemal immunochromatographic strip assay (on-site ICS)-compared to the current practice (off-site RPR/TPHA).FINDINGS:
With antenatal active syphilis prevalence of 6.3%, the incremental cost-effectiveness of on-site ICS in averting congenital infections was estimated to be USD104, averting 82% of cases expected in absence of a program. The incremental cost-effectiveness of off-site RPR/TPHA was USD82 but would avert only 55% of congenital syphilis cases. On-site RPR was dominated by the other screening strategies.CONCLUSIONS:
In settings of high maternal syphilis prevalence, on-site antenatal screening with ICS is a cost-effective approach to reduce the incidence of congenital syphilis.
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Bases de datos:
MEDLINE
Asunto principal:
Complicaciones Infecciosas del Embarazo
/
Diagnóstico Prenatal
/
Sífilis Congénita
/
Sífilis
/
Sistemas de Atención de Punto
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Evaluation_studies
/
Health_economic_evaluation
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
/
Screening_studies
Límite:
Female
/
Humans
/
Newborn
/
Pregnancy
País/Región como asunto:
Africa
Idioma:
En
Revista:
Sex Transm Dis
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos