[Femoropopliteal arterial thrombosis in a young patient with heterozygous V Leiden factor mutation. Case report]. / Trombosi arteriosa femoro-poplitea in giovane portatore di mutazione eterozigote per il fattore V di Leiden. Caso clinico.
Minerva Med
; 98(1): 77-80, 2007 Feb.
Article
en It
| MEDLINE
| ID: mdl-17372584
ABSTRACT
Activated C protein resistance is a common coagulation defect caused by factor V Leiden mutation and is associated with an augmented risk of predominantly venous thrombosis. Augmented tendency to arterial thrombosis is sporadically reported. This case report describes femoropopliteal thrombosis in a young patient with heterozygous V Leiden factor mutation. Progressive thrombotic occlusion required amputation of the forefoot which resulted in stump dehiscence. Poor blood supply to the perilesional substrate delayed wound healing. An optimal though not yet definitive result was achieved after months of accurate medication. The criticality of lower limb ischemia in an otherwise healthy young patient underscores the grave impact this condition can have on the patient's quality of life and on health care costs.
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Bases de datos:
MEDLINE
Asunto principal:
Arteria Poplítea
/
Trombosis
/
Factor V
/
Arteria Femoral
/
Mutación
Límite:
Adult
/
Humans
/
Male
Idioma:
It
Revista:
Minerva Med
Año:
2007
Tipo del documento:
Article
País de afiliación:
Italia