Liver resection in elderly: comparative study between younger and older than 70 years patients. Outcomes and implications for therapy.
G Chir
; 28(11-12): 419-24, 2007.
Article
en En
| MEDLINE
| ID: mdl-18035008
ABSTRACT
BACKGROUND AND AIM:
to identify the factors that could influence the outcome of the old aged patients underwent liver resection for hepatocellular carcinoma (HCC) or colorectal liver metastases (LMCRC). PATIENT ANDMETHODS:
the Authors identified 51 patients older 70 years-old over 12-years period underwent resection for HCC (n 26) or for LMCRC (n 25). This group was compared with a cohort of 93 patients younger than 70 years who underwent resections in the same period. We have evaluated the results in terms of peroperative morbidity and mortality.RESULTS:
the mean age of 51 elderly patients was 74 years-old. Thirty-five were treated with anatomical resection. Cirrhosis was present in 26 patients while 27 had co-morbidities. Thirteen patients developed complications and the mean age of these were 76 years compared with 73 of the patients who have not (p= .01). No mortality was registered. The cirrhosis, blood transfusions, anatomical resection and diameter of the lesion did not influence the outcome.CONCLUSIONS:
our results indicate the age per se should not be considered a contraindication for surgery, that proved to be safe and curative therapy, but showed that old age, using 75 years as a cut-off, in association with at least one comorbid medical condition could be considered as relevant factor of morbidity.
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Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Colorrectales
/
Carcinoma Hepatocelular
/
Hepatectomía
/
Neoplasias Hepáticas
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
G Chir
Año:
2007
Tipo del documento:
Article
País de afiliación:
Italia