Developmental mismatch: consequences for later cardiorespiratory health.
BJOG
; 115(2): 149-57, 2008 Jan.
Article
en En
| MEDLINE
| ID: mdl-18081597
ABSTRACT
Clinical and epidemiological studies have established that people who were small at birth and had poor infant growth have an increased risk of adult cardiovascular and respiratory disease, particularly if their restricted early growth is followed by accelerated childhood weight gain. This relationship extends across the normal range of infant size in a graded manner. The 'mismatch hypothesis' proposes that ill health in later life originates through developmental plastic responses made by the fetus and infant; these responses increase the risk of adult disease if the environment in childhood and adult life differs from that predicted during early development.
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Bases de datos:
MEDLINE
Asunto principal:
Recién Nacido de Bajo Peso
/
Enfermedades Cardiovasculares
/
Discapacidades del Desarrollo
/
Enfermedades Pulmonares
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
BJOG
Asunto de la revista:
GINECOLOGIA
/
OBSTETRICIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Reino Unido