Results of colestipol therapy in Type II hyperlipoproteinemia.
Atherosclerosis
; 24(1-2): 129-40, 1976.
Article
en En
| MEDLINE
| ID: mdl-182181
ABSTRACT
Twenty-five patinets with well defined Type ii hyperlipoproteinemia were treated with a divided 15 g daily dose of colestipol, a bile acid sequestrant, for periods of up to 20 months. The patients were divided into 3 groups Those with no obvious sequelae, those with arcus corneae, xanthomas, and/or xanthelasmas only, and those with atherosclerotic complications. Colestipol lowered plasma cholesterol in all 3 groups, but reduced it to normal or near-normal levels in only 9 of the 25 patients (36%). The response of plasma triglycerides was highly varible; the mean for each group was elevated by the drug. Colestipol was well-tolerated and its effect did not diminish with time. It is a useful drug in the treatment of hypercholesterolemia.
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Bases de datos:
MEDLINE
Asunto principal:
Poliaminas
/
Colestipol
/
Hipercolesterolemia
/
Hiperlipidemias
/
Lipoproteínas LDL
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Atherosclerosis
Año:
1976
Tipo del documento:
Article