Flattened cortical maps of cerebral function in the rat: a region-of-interest approach to data sampling, analysis and display.
Neurosci Lett
; 434(2): 179-84, 2008 Mar 28.
Article
en En
| MEDLINE
| ID: mdl-18325664
ABSTRACT
We describe a method for the measurement, analysis and display of cerebral cortical data obtained from coronal brain sections of the adult rat. In this method, regions-of-interest (ROI) are selected in the cortical mantle in a semiautomated fashion using a radial grid overlay, spaced in 15 degrees intervals from the midline. ROI measurements of intensity are mapped on a flattened two-dimensional surface. Topographic maps of statistical significance at each ROI allow for the rapid viewing of group differences. Cortical z-scores are displayed with the boundaries of brain regions defined according to a standard atlas of the rat brain. This method and accompanying software implementation (Matlab, Labview) allow for compact data display in a variety of autoradiographic and histologic studies of the structure and function of the rat brain.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Programas Informáticos
/
Mapeo Encefálico
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Corteza Cerebral
Límite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos